Small Bowel Transplant Rejection

 Many people suffering from Crohn's Disease have tried many different things to treat their illness, including prescription medications. Some even consider surgery as their only option. However, even though surgery may be an effective way to remove Crohn's Disease's symptoms, it still has its share of side effects and it can lead to serious complications including Small Bowel Infection (SBI).

It is important to note that despite how positive these results may appear, there are still some patients who suffer from small bowel transplants that do not respond to the medication. In a small bowel transplant, typically the lining of the small bowel is removed and substituted with a collagen-based gel. This gel is then inserted into the abdominal cavity and the remainder of the colon is left intact. For patients who are not treated with high-potency antibiotics, it is possible for a small bowel transplant rejection to occur. The key is to treat the infection before it develops into something more serious, the patient will be able to avoid having to go through further surgical treatments.



In cases where a small bowel transplant rejection occurs, the samples taken from the patient will be sent to diagnostic laboratories for further analysis. The microbiology labs will first look for any microbial or allergen elements in the samples taken from the patient. Oftentimes, it is bacteria or allergy symptoms that are the root cause of SBI. If bacterial cultures are detected, the laboratories can perform further tests to determine which specific species are causing the problem. From here, the doctors will be able to prescribe antibiotics that are specifically designed to prevent the bacteria from spreading and causing further problems.

Unfortunately, in some cases, these antibiotics can have severe side effects and hence they are prescribed on a case-by-case basis. The doctors will also try to use immune suppressive drugs to help fight off any further infections that may arise in the patient. Abo-compatible grafts will also be analyzed under a microscope to make sure that there is no other microscopic organism that could cause problems in the patient's liver or small bowel transplantation. These factors can make the identification process more difficult.

Small intestine and colon transplants are generally performed on patients who have been diagnosed with severe chronic disorders such as multiple sclerosis, Crohn's disease, hepatitis C, ulcerative colitis or other similar conditions. However, small bowel transplantation and intestinal transplantation (small intestinal bypass graft) are becoming more widely used for patients who have had surgery for cancer treatments, heart transplants, or any type of digestive disorders. 

In addition, immune suppressive drugs may be prescribed in certain instances. With immune compromising conditions such as HIV and AIDS, doctors may use immune suppressive drugs to prevent the rejection of transplanted organs. This is often referred to as antineo plastic drugs. The process of immune suppression often involves the use of an enteric coated vaccine called the poisson test. The name poisson refers to the first value on a bio-metric test, which represents the percentage of individuals with HIV infection who may produce antibodies to the virus. Antibodies to HIV can be detected in the blood of individuals who may not have developed an HIV infection but who still received a positive test result after being vaccinated with live virus particles. You can also visit websites like plexision.com to know more about other factors related to small bowel transplant rejection.


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